Group of action: Agents affecting musculo-skeletal system

Active ingredient: Diclofenac sodium

Dosage form: Rectal suppositories

Pharmacotherapeutic group: Nonsteroidal anti-inflammatory and antirheumatic agents.

ATC code: M01AB05

RX/OTC: RX

• Inflammatory and degenerative forms of rheumatism, rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, spondylitis including;
• spine pain syndromes; extra-articular rheumatism of soft tissues;
• acute gout;
• post-traumatic and postoperative pain, accompanied by inflammation and edema, particularly after dental or orthopedic surgery; migraine attacks;
• gynecological diseases accompanied by pain and inflammation, such as primary dysmenorrhea and adnexitis;
• as an adjunct in severe inflammatory diseases of ENT - organs, accompanied by painful sensations, such as pharyngitis, tonsillitis, otitis media.

• Hypersensitivity to the active substance or to any - or excipient;
• bleeding or perforation of the gastro - intestinal tract in history related to previous NSAIDs therapy;
• the active form of peptic ulcer / bleeding or recurrent peptic ulcer / bleeding history (two or more distinct episodes of established ulceration or bleeding);
• inflammatory bowel disease (e.g. Crohn's disease or ulcerative colitis);
• last 3 months of pregnancy;
• proctitis;
• severe liver, kidney or heart failure;
• congestive heart failure (NYHA II-IV);
• coronary heart disease in patients with angina pectoris, myocardial infarction;
• cerebrovascular disease in patients who have had a stroke or have episodes of transient ischemic attacks;
• peripheral arterial disease; the treatment of perioperative pain in coronary artery bypass surgery (or the use of cardiopulmonary bypass);

The drug is contraindicated in patients who have a response to acetylsalicylic acid or other NSAIDs as attacks of asthma, urticaria, angioedema, or acute rhinitis.